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Stereoselective Synthesis of γ‐Butyrolactones Subunit of Polycavernoside A
Author(s) -
Kadari Sudhakar,
Yerrabelly Hemasri,
Gogula Thirupathi,
Erukala Yadaiah Goud,
Yerrabelly Jayaprakash Rao,
Begari Prem Kumar
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3240
Subject(s) - chemistry , stereoselectivity , ring closing metathesis , yield (engineering) , stereochemistry , protein subunit , metathesis , sharpless epoxidation , combinatorial chemistry , organic chemistry , catalysis , polymerization , biochemistry , polymer , metallurgy , materials science , gene
An efficient and versatile linear synthesis of γ‐butyrolactone subunit of polycavernolide A has been reported in 14.2% overall yield with 10 linear steps by employing Sharpless asymmetric epoxidation, ring‐closing metathesis, and diastereoface selective hydrogenation.