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Synthesis and Characterization of Some Novel Phosphorylated 4‐Oxo‐2‐phenylquinazolines
Author(s) -
Assiri Mohammed A.,
Ali Tarik E.,
ElEdfawy Somaya M.,
Yahia I. S.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3233
Subject(s) - chemistry , phosphorylation , characterization (materials science) , combinatorial chemistry , stereochemistry , nanotechnology , biochemistry , materials science
Some novel phosphines, aminophosphines and their oxides, and derived phosphorus acids bearing 4‐oxo ‐ 2‐phenylquinazolin‐3‐yl moiety were synthesized. The methodology depended on the reaction of each 2‐phenylquinazolin‐4(3 H )‐one ( 1 ) and 3‐amino‐2‐phenyl‐quinazolin‐4(3 H )‐one ( 2 ) with (Ph) 2 PCl, PhPCl 2 , and PhP (O)Cl 2 in different ratios. The synthesized compounds were characterized by elemental analysis and spectral tools.