Premium
Microwave‐Assisted Synthesis and Characterization of Novel Sulfonamide‐β‐Lactam Conjugates
Author(s) -
Brown David P.,
Saklani Pooja,
Luo Jiawei
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3219
Subject(s) - chemistry , sulfonamide , lactam , conjugate , microwave irradiation , combinatorial chemistry , microwave , stereochemistry , organic chemistry , catalysis , physics , quantum mechanics , mathematical analysis , mathematics
New sulfonamide‐β‐lactam molecular conjugates 3 ( a – l ) have been generated through microwave‐assisted synthesis. β‐Lactams 1 ( a – e ) reacted with selected sulfonamides under microwave irradiation in the presence of KI and mediated by K 2 CO 3 to afford conjugates 3 ( a – l ). All new compounds were structurally authenticated by spectroscopic and elemental analyses.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom