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Green Synthesis, Antibacterial, and Antifungal Activities of 1,3,4‐Oxadiazines
Author(s) -
Eissa Fayez M.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3194
Subject(s) - chemistry , antifungal , context (archaeology) , antibacterial activity , elemental analysis , proton nmr , green chemistry , combinatorial chemistry , nuclear chemistry , organic chemistry , stereochemistry , bacteria , microbiology and biotechnology , molecule , paleontology , genetics , supramolecular chemistry , biology
1,3,4‐Oxadiazine derivatives were prepared via green and more sustainable procedure employing Grinding Chemistry. The green context of the procedure was evaluated by comparing its components with that of the conventional one. The antibacterial and antifungal activities of all the synthesized compounds were evaluated against some bacterial and fungal strains and showed promising results. The structures of the resulted compounds were identified and confirmed by elemental analysis and mass, 1 H‐NMR, and 13 C‐NMR spectroscopies.