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A Review: Synthesis and Medicinal Importance of Nicotinonitriles and Their Analogous
Author(s) -
Gouda Moustafa A.,
Hussein Belal H. M.,
Helal Mohamed H.,
Salem Mohammed A.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3188
Subject(s) - chemistry , reactivity (psychology) , biochemical engineering , combinatorial chemistry , organic chemistry , traditional medicine , nanotechnology , alternative medicine , medicine , materials science , pathology , engineering
The biological, therapeutic, and medicinal properties of nicotinonitriles (cyanopyridines) and its analogues have prompted enormous research aimed at developing synthetic routes to these heterocyles. This review presents a systematic and comprehensive survey of the method of preparation, the chemical reactivity, and biological properties associated with this system.