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A Facile Synthesis of Xanthene‐1,8(2 H )‐dione Derivatives by Using Tetrapropylammonium Bromide as Catalyst
Author(s) -
Poursattar Marjani Ahmad,
Abdollahi Sima,
Ezzati Mahnaz,
NematiKande Ebrahim
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3164
Subject(s) - xanthene , dimedone , chemistry , catalysis , bromide , cyclohexane , ethanol , condensation , organic chemistry , medicinal chemistry , physics , thermodynamics
Several new derivatives of 9‐aroyl‐3,4,5,6,7,9‐hexahydro‐1 H ‐xanthene‐1,8(2 H )‐dione have been synthesized in yields varying from high to excellent by the condensation reaction of arylglyoxals with 1,3‐diketones (cyclohexane‐1,3‐dione or dimedone) and TPAB as an inexpensive, recoverable, and non‐toxic catalyst in the presence of ethanol/water under reflux conditions.