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Green Synthesis of 1,2,4,5‐Tetrasubstituted and 2,4,5‐Trisubstituted Imidazole Derivatives Involving One‐pot Multicomponent Reaction
Author(s) -
Bansal Ravi,
Soni Pradeep K.,
Halve Anand K.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3160
Subject(s) - chemistry , imidazole , catalysis , reaction conditions , combinatorial chemistry , solvent , organic chemistry
Sodium lauryl sulfate has been found convenient, versatile, and eco‐friendly catalyst for the synthesis of 1,2,4,5‐tetrasubstituted and 2,4,5‐trisubstituted imidazole derivatives by one‐pot multicomponent reactions at 80°C using water as solvent. This protocol afforded advantages, that is, the metal‐free reaction, purification of products by non‐chromatographic method, and excellent yields.