Premium
Synthesis of 6‐Oxo‐1,2,3,4,6,7,12,12 b ‐octahydroindolo[2,3‐ a ]quinolizine
Author(s) -
Tompkins David C.,
Reilly Laurence W.,
Nelson Randall B.,
Dolby Lloyd J.,
Gribble Gordon W.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3130
Subject(s) - chemistry , phenylhydrazine , alkaloid , derivative (finance) , stereochemistry , organic chemistry , financial economics , economics
An efficient synthesis of 6‐oxo‐1,2,3,4,5,7,12,12 b ‐octahydroindolo[2,3‐ α ]quinolizine from 2‐acetylpyridine and phenylhydrazine is described. This derivative of the natural alkaloid desbromoarborescidine A is an important entry point to the sarpagine‐vobasine family of plant alkaloids.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom