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Recent Advances in Imidazo[5,1‐ f ][1,2,4]triazin‐4(3 H )‐ones Chemistry: An Overview of the Synthetic Routes to Vardenafil and Its Analogues
Author(s) -
Gouda Moustafa A.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3101
Subject(s) - chemistry , vardenafil , combinatorial chemistry , stereochemistry , sildenafil , tadalafil , medicine
The biological and medicinal properties of imidazo[5,1‐ f ][1,2,4]triazin‐4(3 H )‐ones and its analogues have prompted enormous research aimed at developing synthetic routes to these heterocycles. This review focuses on the chemical properties associated with these systems.