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Glycine‐catalyzed easy and efficient one‐pot synthesis of polyhydroquinolines through Hantzsch multicomponent condensation under controlled microwave
Author(s) -
Singh Satish Kumar,
Singh Krishnd
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.308
Subject(s) - chemistry , glycine , microwave irradiation , microwave , catalysis , condensation , condensation reaction , one pot synthesis , organic chemistry , combinatorial chemistry , reaction conditions , amino acid , biochemistry , physics , quantum mechanics , thermodynamics
Glycine, a novel heterogeneous organocatalyst, is found to be highly effective for the synthesis of polyhydroquinoline derivatives in a one‐pot multicomponent reaction via Hantzsch condensation under controlled microwave (MW) irradiation. The combination of glycine and MW has promising features for the reaction response, such as the shortest reaction time, excellent product yields, and simple work‐up of the products. J. Heterocyclic Chem., (2010).