Premium
A Green Synthesis of Highly Functionalized 3‐amino‐2‐phenylsulfonyl‐1‐alkyl/aryl‐1 H ‐pyrazolo[1,2‐ b ]phthalazine‐5,10‐diones and Their Reduction and Photophysical Studies
Author(s) -
Shi Xin,
Ding Maohua,
Li Conghao,
Wang Wang,
Guo Hongyun
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3061
Subject(s) - chemistry , phthalazine , alkyl , acetonitrile , aryl , catalysis , condensation reaction , condensation , medicinal chemistry , organic chemistry , combinatorial chemistry , physics , thermodynamics
3‐Amino‐2‐benzenesulfonyl‐1‐alkyl/aryl‐1H‐pyrazolo[1,2‐b]phthalazine‐5,10‐dione derivatives were synthesized by the one‐pot, three‐component condensation of phthalhydrazide, aldehydes, and (phenylsulfonyl)acetonitrile in EtOH using 2‐hydroxyethylammonium acetate as catalyst. The advantages of this method include environmental friendliness, easy work‐up, and excellent yields. The reduction of some products and photophysical properties were also investigated.