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Spiro[4 H ‐2,3‐dihydropyran‐3,3′‐oxindoles] derived from 1,2,3,4‐tetrahydroquinoline
Author(s) -
Saatluo Bahman Ebrahimi,
Baradarani Mehdi M.,
RóżyckaSokołowska Ewa,
Bałczewski Piotr,
Joule John A.
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3030
Subject(s) - chemistry , dihydropyran , knoevenagel condensation , hemiacetal , quinoline , stereochemistry , medicinal chemistry , organic chemistry , catalysis
Knoevenagel condensation of 5,6‐dihydro‐4 H ‐pyrrolo[3,2,1‐ ij ]quinoline‐1,2‐dione 3 with aryl cyanomethyl ketones 9 generates 3‐(aroyl(cyano)methylidene)oxindoles 10 that react with cyclic 1,3‐diketones 11 to generate polycyclic hemiacetal spiro[4 H ‐2,3‐dihydropyran‐3,3′‐oxindoles] 13 .
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