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Green Synthesis of 6‐Aryl‐5,6‐dihydrobenzo[4,5]imidazo[1,2‐ c ]quinazoline Derivatives in Ionic Liquid under Catalyst‐free Conditions
Author(s) -
Chen DongSheng,
Liu ShuJun,
Lu WenQiang,
Wang XiangShan
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3020
Subject(s) - chemistry , quinazoline , ionic liquid , aniline , catalysis , aryl , ionic bonding , medicinal chemistry , organic chemistry , combinatorial chemistry , ion , alkyl
Using ionic liquids as green media, a series of 6‐arylbenzo[4,5]imidazo[1,2‐ c ]quinazoline derivatives is synthesized via a reaction of 2‐(1 H ‐benzo[ d ]imidazol‐2‐yl)aniline and benzaldehydes in the air. While the intermediate products of 6‐aryl‐5,6‐dihydrobenzo[4,5]imidazo[1,2‐ c ]quinazolines were obtained in high yields at the same conditions under nitrogen protection.