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Utility of N ′‐((2‐chloroquinolin‐3‐yl)methylene)‐2‐cyanoacetohydrazide as a Source of Biologically Active Novel Heterocycles
Author(s) -
Elsayed Galal A.,
Omara Samir A.,
Kamel Rabaa M.
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2965
Subject(s) - chemistry , quinoline , antimicrobial , methylene , biological activity , combinatorial chemistry , agar , organic chemistry , stereochemistry , bacteria , biochemistry , in vitro , biology , genetics
The title compound is used as a precursor in synthesis of differently sized heterocyclic systems bearing quinoline moeity. Investigation of antimicrobial activity of the new products was evaluated using agar well diffusion method against six reference microbial isolates. Most of the new compounds are potent as antimicrobial agents.