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Ring Transformation of a 2(3 H )‐furanone Derivative into Oxazinone and Pyrimidinone Heterocycles
Author(s) -
Hashem Ahmed I.,
AbouElmagd Wael S. I.,
ElZiaty Ahmed K.,
Ramadan Sayed K.
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2937
Subject(s) - chemistry , azide , benzene , furan , ring (chemistry) , thermal decomposition , derivative (finance) , decomposition , benzene derivatives , combinatorial chemistry , transformation (genetics) , organic chemistry , chemical synthesis , economics , in vitro , gene , biochemistry , financial economics
The conversion of the 2(3 H )‐furanone into the oxazinone and pyrimidinone derivatives is studied. A 2‐(furan‐2‐ylmethylene)‐4‐oxo‐4‐phenylbutanoyl azide 3 was synthesized to carry out these conversions through its thermolysis in dry benzene and/or base‐catalyzed decomposition of this azide in the presence of different amines. The structures of all compounds were demonstrated from their spectral data and elemental analyses.