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Microwave‐Assisted, One‐Pot Multicomponent Synthesis of Some New Cyanopyridines
Author(s) -
Amer Amer A.,
Abdelhamid Antar A.
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2926
Subject(s) - malononitrile , chemistry , ammonium acetate , alkoxide , microwave , component (thermodynamics) , ammonium , organic chemistry , catalysis , high performance liquid chromatography , physics , quantum mechanics , thermodynamics
An efficient and facile synthesis of cyanopyridines via a one‐pot four‐component reaction of aromatic aldehydes, acetophenones, malononitrile, or 2‐aminoprop‐1‐ene‐1,1,3‐tricarbonitrile in presence of sodium alkoxide or ammonium acetate under both microwave and thermal reaction conditions was introduced.