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Facile Synthesis and Bioactivity of Novel N , N′ ‐disubstituted‐1,2,3,4‐tetrahydroquinoxalines
Author(s) -
Fu Ying,
Wang JingYi,
Chen WenGeng,
Li Yu,
Zhao LiXia,
Gao Shuang,
Ye Fei
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2911
Subject(s) - chemistry , acetochlor , acylation , mass spectrometry , high resolution , proton nmr , resolution (logic) , carbon 13 nmr , stereochemistry , combinatorial chemistry , organic chemistry , chromatography , remote sensing , artificial intelligence , pesticide , computer science , agronomy , biology , geology , catalysis
A series of novel N , N' ‐disubstituted‐1,2,3,4‐tetrahydroquinoxalines were designed and synthesized by cyclization and acylation. The structures of all the novel compounds were confirmed by IR, 1 H NMR, 13 C NMR, and high‐resolution mass spectrometry. The configuration of 4d was determined by X‐ray diffraction. The preliminary biological tests showed that all the products could protect maize against the injury caused by acetochlor to some extent.