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A simple, mild, and efficient procedure for high‐yield synthesis of benzimidazoles using coppertriflate as catalyst
Author(s) -
Chari M. Adharvana,
Sadanandam P.,
Shobha D.,
Mukkanti K.
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.287
Subject(s) - chemistry , acetonitrile , yield (engineering) , catalysis , trifluoromethanesulfonate , solvent , organic chemistry , reflux , combinatorial chemistry , metallurgy , materials science , medicine , disease , pathology
Copper triflate has been found to be an efficient catalyst for the synthesis of benzimidazoles from o ‐phenylenediamine and aldehydes at reflux temperature under acetonitrile solvent. This new method consistently has the advantage of excellent yields (74–95%) at reflux temperature. J. Heterocyclic Chem., 2010.