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Cardiovascular Calcium Channel Blockers: Historical Overview, Development and New Approaches in Design
Author(s) -
Drapak Iryna,
Perekhoda Lina,
Tsapko Tetiana,
Berezniakova Natalia,
Tsapko Yevgen
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2837
Subject(s) - chemistry , dihydropyridine , calcium channel , calcium , pharmacology , organic chemistry , medicine
The data on historical development and modern design approaches for calcium channels blockers (mainly L‐type) are summarized in this review. Chemical groups such as dihydropyridine and hydropyrimidine derivatives, as well as phenylalkylamines and benzothiazepines are discussed.