Synthesis of Novel 7‐methylene‐6,7‐dihyrobenzo[f]Benzo[4,5]Imidazo[1,2‐d][1,4]Oxazepines  via  Base‐mediated Regioselective Intramolecular Hydroamination | Zendy

Yavari Hossein | Zendy; Alinezhad Heshmatollah | Zendy; Shafiee Abbas | Zendy

Premium

Synthesis of Novel 7‐methylene‐6,7‐dihyrobenzo[f]Benzo[4,5]Imidazo[1,2‐d][1,4]Oxazepines via Base‐mediated Regioselective Intramolecular Hydroamination

Author(s) -

Yavari Hossein,

Alinezhad Heshmatollah,

Shafiee Abbas

Publication year - 2017

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.2833

Subject(s) - chemistry , hydroamination , regioselectivity , intramolecular force , potassium carbonate , imidazole , methylene , medicinal chemistry , stereochemistry , base (topology) , combinatorial chemistry , catalysis , organic chemistry , mathematical analysis , mathematics

A versatile and transition metal‐free approach for the synthesis of new 7‐methylene‐6,7‐dihyrobenzo[f]benzo[4,5]imidazo[1,2‐d][1,4]oxazepines were developed by an efficient 7‐exo‐dig regioselective hydroamination of 2‐(2‐(prop‐2‐yn‐1‐yloxy)phenyl)‐1H‐benzo[d]imidazole in the presence of potassium carbonate in DMF at 90°C.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research