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Convenient Structural Diversity‐Guided Synthesis of Functionalized Sulfur‐Containing Heterocycles via α‐Substituted Cyanoacetamides
Author(s) -
Ke Shaoyong
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2792
Subject(s) - isothiazole , chemistry , thiazolidine , thiazine , combinatorial chemistry , sulfur , molecule , drug discovery , computational chemistry , stereochemistry , organic chemistry , biochemistry
A convenient molecular diversity‐oriented synthesis of various functional sulfur‐containing heterocyclic scaffolds mainly including isothiazole, 2 H ‐1,3‐thiazine, and thiazolidine via different methods from α‐substituted cyanoacetamides is described. The target molecules have been identified on the basis of analytical spectral data, which may serve as useful structural subunits in the fields of drug discovery.