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One‐pot Syntheses of Some New 2,4(1 H ,3 H )‐quinazolinedione Derivatives in the Absence of Catalyst
Author(s) -
Mohammadi Ali Asghar
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2778
Subject(s) - chemistry , yield (engineering) , catalysis , amine gas treating , condensation , primary (astronomy) , organic chemistry , one pot synthesis , combinatorial chemistry , medicinal chemistry , materials science , physics , astronomy , metallurgy , thermodynamics
A facile, rapid and one‐pot procedure for the synthesis of some new 2,4(1 H ,3 H )‐quinazolinediones is described. The method involves the one‐pot condensation of isatoic anhydride, primary amine and carbonyl diimidazole (CDI) in the absence of organic or inorganic catalyst. It affords the corresponding product in high yield.