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N,N,N′,N′ ‐Tetrabromobenzene‐1,3‐disulfonamide Catalyzed Synthesis of New Spiro[chroman‐3,2′‐chromeno[2,3‐ b ]furan]‐2,4,4′‐(3′ H )‐trione Derivatives
Author(s) -
GhorbaniVaghei Ramin,
Malaekehpoor Seyedeh Mina
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2769
Subject(s) - chemistry , furan , catalysis , knoevenagel condensation , tandem , reusability , organic chemistry , combinatorial chemistry , solvent , reaction conditions , materials science , software , computer science , composite material , programming language
An efficient approach for one‐pot synthesis of biologically active new spiro[chroman‐3,2′‐chromeno[2,3‐ b ]furan]‐2,4,4′‐(3′ H )‐trione derivatives from tandem Knoevenagel–Michel addition–heterocyclization reaction between 4‐hydroxycumarin and various aldehydes in the presence of N,N,N ′ ,N ′‐tetrabromobenzene‐1,3‐disulfonamide as an efficient catalyst at ambient temperature under solvent‐free conditions was reported. Simple procedure, high yields, easy work‐up, and reusability of the catalyst are the significant advantages of this process.