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Synthesis of Isoxazole‐Linked Norcantharidin Analogues of Substituted Chromones
Author(s) -
Wang Wei,
Deng Liping,
Hu Chunqi,
Zhang Yaohong,
Li Yan,
Zuo Shufeng
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2767
Subject(s) - chemistry , chromone , isoxazole , cycloaddition , ring (chemistry) , chloramine t , 1,3 dipolar cycloaddition , stereochemistry , combinatorial chemistry , organic chemistry , medicinal chemistry , catalysis
Eighteen novel norcantharidin derivatives, which were substituted by chromone ring, were synthesized in a single step by the [3 + 2] 1,3‐dipolar cycloaddition reaction with three oximes in the presence of chloramine‐T when compared with the conventional method.