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An Efficient One‐Pot Four‐Component Synthesis of Some New Spirooxindole Dihydropyridine Using Alum as a Heterogeneous Green Catalyst
Author(s) -
Mohammadi Ali A.,
Taheri Salman,
Amouzegar Ali
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2757
Subject(s) - chemistry , alum , indoline , catalysis , ketene , pyridine , dihydropyridine , one pot synthesis , nitro , component (thermodynamics) , organic chemistry , medicinal chemistry , combinatorial chemistry , alkyl , physics , thermodynamics , calcium
4‐Nitro‐2,3‐dihydrospiro[imidazo[1,2‐ a ]indeno[2,1‐ e ]pyridine‐5,3′‐indoline]‐2′,6(1 H )‐dione derivatives have been synthesized in good yields in a one‐pot four‐component, and efficient process by reaction of corresponding isatins, 1,3‐indandione, diamine, and nitro ketene dithioacetal in the presence of KAl(SO 4 ) 2 .12H 2 O (Alum) as a nontoxic and easily available heterogeneous green catalyst.