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Amidrazones and 2‐Acetylcyclopentanone in the Synthesis of Cyclopenta[ e ][1,3,4]Oxadiazepines
Author(s) -
Aly Ashraf A.,
Ishak Esam A.,
Ramadan Mohamed,
Elkanzi N. A. A.,
El-Reedy Ahmed A. M.
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2727
Subject(s) - chemistry , elemental analysis , nuclear magnetic resonance spectroscopy , computational chemistry , mass spectrum , infrared spectroscopy , mass spectrometry , stereochemistry , organic chemistry , chromatography
Amidrazones reacted with 2‐acetylcyclopentanone at room temperature to give cyclopenta[ e ]‐[1,3,4]oxadiazepines. The structure of the obtained products was proved by IR, mass, and NMR spectra and elemental analyses. Two‐dimensional NMR spectroscopy was used to differentiate between other possible isomers. The reaction mechanism is also discussed.