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Microwave‐Promoted Pd‐Catalyzed Synthesis of Dibenzofurans from Ortho ‐Arylphenols
Author(s) -
Schmidt Bernd,
Riemer Martin
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2704
Subject(s) - chemistry , catalysis , microwave irradiation , aryl , phenols , microwave heating , organic chemistry , microwave , oxidative coupling of methane , palladium , coupling reaction , combinatorial chemistry , medicinal chemistry , suzuki reaction , alkyl , physics , quantum mechanics
ortho ‐Aryl phenols, synthesized via protecting group free Suzuki–Miyaura coupling of ortho ‐halophenols and arene boronic acids, undergo a cyclization to dibenzofurans via oxidative C–H activation . The reaction proceeds under microwave irradiation in short reaction times using catalytic amounts of Pd(OAc) 2 without additional ligands.