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Iminophosphoranes in Heterocyclic Synthesis: A Facile Synthesis of Pyrido[4,3‐ D ]Pyrimidine and Pyrido[4,3‐ D ][1,3]Oxazine Derivatives via Intermolecular aza‐Wittig Reactions
Author(s) -
Omran Omran A.,
Sayed Samia M.,
Raslan Mohamed A.
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2680
Subject(s) - chemistry , annulation , wittig reaction , pyrimidine , isocyanate , tandem , intermolecular force , combinatorial chemistry , organic chemistry , stereochemistry , molecule , catalysis , materials science , composite material , polyurethane
A novel series of pyrido[4,3‐ d ]pyrimidine and pyrido[4,3‐ d ][1,3]oxazine derivatives were synthesized via tandem aza‐Wittig and annulation reactions with the corresponding iminophosphoranes, aromatic isocyanate, and amines. All newly synthesized compounds were elucidated by considering the data of both elemental and spectral analysis.