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Investigation of the Reactions of Indole‐2,3‐diones with Biuret: A Novel Approach for the Synthesis of Spiro[indole‐triazines]
Author(s) -
Kumar Deepak,
Sharma Lokesh K.,
Sharma Kanti,
Jain Renuka
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2623
Subject(s) - chemistry , biuret test , indole test , organic chemistry , carbon 13 nmr , solvent , stereochemistry , medicinal chemistry , urea
Reactions of indole‐2,3‐diones with biuret afforded 1,3‐dihydro‐3‐ureidoformimido‐2 H ‐indol‐2‐ones and spiro[3 H ‐indole‐3,2′(1′ H )‐(1,3,5)triazine]‐2,4′,6′(1 H ,3′ H ,5′ H )‐triones indicated these to be solvent dependent. The chemical structures of the products were elucidated by their comprehensive spectroscopic (IR, 1 H‐NMR, 13 C‐NMR, 19 F‐NMR, and Mass) as well as analytical analysis.