Premium
N ‐Bromosulfonamides catalyzed synthesis of new spiro [indoline‐3,4 ' ‐pyrano[2,3‐ c ]pyrazole] derivatives
Author(s) -
GhorbaniVaghei Ramin,
Malaekehpoor Seyedeh Mina
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2605
Subject(s) - indoline , chemistry , malononitrile , pyrazole , catalysis , tandem , benzene , organic chemistry , pyran , medicinal chemistry , materials science , composite material
An efficient approach for the synthesis of pharmacologically important spiro[indoline‐3,4'‐pyrano[2,3‐c]pyrazole] derivatives from tandem, four component reaction of various hydrazines, isatins, β‐ketoesters, and malononitrile or methyl(ethyl)cyanoester in the presence of N,N,N',N'‐tetrabromobenzene‐1,3‐disulfonamide [ TBBDA ] and poly(N,N'‐dibromo‐N‐ethyl‐benzene‐1,3‐disulfonamide) [ PBBS ] as efficient organocatalysts was reported.