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Synthesis of New Polysubstituted Indolizines from Pyridine, Bromonitromethane, and Dialkyl Acetylenedicarboxylates
Author(s) -
Piltan Mohammad,
Kalantari Shahin
Publication year - 2017
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2582
Subject(s) - chemistry , pyridine , organic chemistry , combinatorial chemistry , medicinal chemistry
An efficient and novel approach to the synthesis of dialkyl 1‐nitroindolizine‐2,3‐dicarboxylates has been described. A one‐pot reaction between a pyridine, dialkyl acetylendicarboxylate, and bromonitromethane leads to dialkyl 1‐nitroindolizine‐2,3‐dicarboxylates in good yields.