Synthesis and Anticancer Activity of Novel  N ‐trisazole/isoxazole Alkyl Functionalized Quinolin‐2(1 H )‐one Derivatives | Zendy

Gaddameedi Jitender Dev | Zendy; Yedla Poornachandra | Zendy; Kuchukulla Ratnakar Reddy | Zendy; Chavva Kurumurthy | Zendy; Pillalamarri Sambasiva Rao | Zendy; Gautham Santhosh Kumar | Zendy; Chityal Ganesh Kumar | Zendy; Banda Narsaiah | Zendy

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Synthesis and Anticancer Activity of Novel N ‐trisazole/isoxazole Alkyl Functionalized Quinolin‐2(1 H )‐one Derivatives

Author(s) -

Gaddameedi Jitender Dev,

Yedla Poornachandra,

Kuchukulla Ratnakar Reddy,

Chavva Kurumurthy,

Pillalamarri Sambasiva Rao,

Gautham Santhosh Kumar,

Chityal Ganesh Kumar,

Banda Narsaiah

Publication year - 2017

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.2566

Subject(s) - isoxazole , chemistry , alkyl , medicinal chemistry , combinatorial chemistry , stereochemistry , triazole , organic chemistry

A series of novel N ‐triazole/isoxazole alkyl quinolin‐2(1 H )‐one derivatives 6a , 6b , 6c , 6d , 6e , 6f , 6g , 6h , 6i , 6j , 6k , 6l , 6m , 9a , 9b , 9c , 9d , and 7a , 7b , 7c , 7d , 7e , 7f , 7g , 7h , 7i , 7j , 7k , 7l , 7m , 7n , 7o , 7p , 7q , 7r were prepared. Compounds 6d and 6k , which showed promising anticancer activity at micromolar concentration, have been identified.

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