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Synthesis and Antifungal Activities of Some New 5,7‐Disubstituted[1,2,4]Triazolo[1,5‐ a ]Pyrimidin‐6‐one Derivatives
Author(s) -
Borthakur Susanta Kumar,
Borthakur Sukanya,
Goswami Debarshi,
Boruah Paran,
Kalita Pabitra Kumar
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2479
Subject(s) - chemistry , ketene , triethylamine , antifungal , triazole , cycloaddition , chloride , rhizoctonia solani , medicinal chemistry , organic chemistry , catalysis , microbiology and biotechnology , horticulture , biology
Synthesis of a new series of [1,2,4]triazolo[1,5‐ a ]pyrimidin‐6‐one by [4 + 2]cycloaddition reaction of 3‐benzylidineamino[1,2,4]triazole with monophenyl ketene and diphenyl ketene generated in situ from phenylacetyl chloride and diphenylacetyl chloride in the presence of triethylamine is described. The newly synthesized compounds were also tested for antifungal activities against Rhizoctonia solani and Trichoderma sp .