Microwave‐assisted  Regioselective Synthesis  of Novel Bis(azoles) and Bis(azoloazines) | Zendy

AlBogami Abdullah S. | Zendy; Mekky Ahmed E. M. | Zendy

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Microwave‐assisted Regioselective Synthesis of Novel Bis(azoles) and Bis(azoloazines)

Author(s) -

AlBogami Abdullah S.,

Mekky Ahmed E. M.

Publication year - 2016

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.2462

Subject(s) - regioselectivity , chemistry , structural isomer , microwave irradiation , cycloaddition , combinatorial chemistry , microwave , computational chemistry , stereochemistry , organic chemistry , catalysis , physics , quantum mechanics

We introduce efficient regioselective synthesis of a series of novel bis(pyrazoles) and bis(isoxazoles) via 1,3‐dipolar cycloaddition reaction under microwave irradiation . Unequivocal structural assignment of the obtained regioisomers was determined utilizing 1 H‐ 13 C HMBC NMR techniques as a valuable tool. A comparative study of the aforementioned reactions was carried out under conventional method as well as under microwave irradiation conditions.

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