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Synthesis, Spectral Characterization, and Antimicrobial Activity of Novel 2,4,6‐Trisubstituted Quinazoline Derivatives by Buchwald and Suzuki Coupling Reactions
Author(s) -
Veena Vani Kotla,
Ramesh Garlapati,
Venkata Rao Chunduri
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2459
Subject(s) - chemistry , quinazoline , antimicrobial , combinatorial chemistry , carbon 13 nmr , proton nmr , stereochemistry , organic chemistry
A series of novel 2,4,6‐trisubstituted quinazoline derivatives were synthesized starting from 2‐amino‐5‐bromobenzoic acid. The structures of the newly synthesized compounds were established by IR, 1 H NMR, 13 C NMR, and mass spectral data. All the compounds were tested for antimicrobial activity .
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