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Synthesis and Herbicidal Evaluation of Novel Uracil Derivatives Containing Benzothiazol‐2‐yl Moiety
Author(s) -
Che JianYi,
Meng XiangSuo,
Xu XiaoYun,
Jiang Shan,
Gu YuCheng,
Shi DeQing
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2453
Subject(s) - moiety , chemistry , uracil , combinatorial chemistry , bioassay , broad spectrum , lead compound , organic chemistry , stereochemistry , biochemistry , in vitro , dna , biology , genetics
In order to search for novel Protox inhibitors with high efficiency, broad‐spectrum activity, and safety to crops, commercially herbicide butafenacil was used as lead compound for further optimization, a series of title compounds 3a , 3b , 3c , 3d , 3e , 3f , 3g , 3h , 3i were designed and synthesized by introducing benzothiazol‐2‐yl moiety into the uracil skeleton. The bioassays indicated that some of the target compounds displayed moderate herbicidal activities in the post‐emergence treatment.