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Synthesis and Insecticidal Efficacy of Novel Bis Quinazolinone Derivatives
Author(s) -
Elshahawi Manal M.,
ELZiaty Ahmed K.,
Morsy Jehan M.,
Aly Aly F.
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2445
Subject(s) - chemistry , quinazolinone , morpholine , hydrazine (antidepressant) , ethanolamine , piperidine , hydrate , hydroxylamine , nucleophile , organic chemistry , diamine , primary (astronomy) , amine gas treating , derivative (finance) , combinatorial chemistry , medicinal chemistry , chromatography , physics , astronomy , financial economics , economics , catalysis
A novel bis benzoxazin‐4‐one derivative has been synthesized and utilized to construct a new series of bis quinazolin‐4(3 H )‐one derivatives via the reactions with different nitrogen nucleophiles namely, primary amines (ammonia, ethanolamine, and 4‐aminoantipyrine), secondary amines (morpholine and piperidine), diamine (o‐phenylenediamine), hydrazine hydrate, and hydroxylamine. The insecticidal efficacy of newly synthesized compounds was also studied. The structural features of the synthesized compounds were assigned by spectral analysis.