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Synthesis of Naphthalene Functionalized Trans ‐2,3‐dihydrofuro[3,2‐ c ]coumarins as Antioxidant and Anthelmintic Agents
Author(s) -
Wadhwa Deepak,
Arora Varun,
Arora Loveena,
Arora Pragi,
Parkash Om
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2431
Subject(s) - chemistry , anthelmintic , triethylamine , acetonitrile , antioxidant , pyridine , naphthalene , organic chemistry , bicyclic molecule , coumarin , catalysis , medicinal chemistry , ecology , biology
A series of trans ‐2,3‐dihydrofuro[3,2‐ c ]coumarins ( 4 ) has been synthesized by a one‐pot multicomponent reaction by aromatic aldehydes, 4‐hydroxycoumarin, α‐tosyloxyketones, and pyridine using triethylamine as catalysts in acetonitrile. The synthesized compounds were then screened for their antioxidant and anthelmintic activities.