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Hydrazononitriles as Precursors for 4‐aminotriazoles and 3‐aminoisoxazoles: One Pot Synthesis of triazolo[1,5‐ a ]quinazoline Derivatives
Author(s) -
Abdelhamid Ismail A.,
Abdelmoniem Amr M.,
Ghozlan Said A. S.,
Butenschön Holger
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2426
Subject(s) - chemistry , hydroxylamine hydrochloride , quinazoline , hydroxylamine , hydrochloride , triazole , 1,2,4 triazole , organic chemistry , combinatorial chemistry , medicinal chemistry
The reaction of various hydrazononitriles with hydroxylamine hydrochloride yielded various products, namely, 3‐aminoisoxazolone, 3‐amino‐1,2,4‐triazole and 4‐amino‐1,2,3‐triazole derivatives depending on the nature of substituents.