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Novel Synthesis of 1,3‐Thiazine and Pyrimidinethione Derivatives from (1‐Aryl ethylidene)hydrazinecarbothioamides and Tetracyanoethylene
Author(s) -
Hassan Alaa A.,
Ibrahim Yusria R.,
ElSheref Essmat M.,
Bräse Stefan
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2350
Subject(s) - tetracyanoethylene , chemistry , thiazine , aryl , combinatorial chemistry , medicinal chemistry , organic chemistry , alkyl
1,3‐Thiazine‐5,6,6‐tricarbonitrile and 2‐thioxo‐2,3‐dihydropyrimidine‐4,5‐dicarbonitriles derivatives were synthesized via interactions between (1‐aryl ethylidene)hydrazinecarbothioamides and tetracyanoethylene to give the derivatives of tetracyanoethane and tricyanovinylation intermediates, followed by heterocyclization . The structures of the products have been confirmed by different spectroscopic analyses. A rational for the formation of the products is presented.