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Convenient Synthesis of Functionalized 3,4,10,11‐tetrahydroindolo[1,2‐a]Quinoxalines Via Three‐component Reaction of Dimedone, 3‐nitrochromenes and Ammonium Acetate
Author(s) -
Fang Jun,
Yan ChaoGuo
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2345
Subject(s) - dimedone , chemistry , ammonium acetate , component (thermodynamics) , ammonium , ethanol , atom economy , organic chemistry , reaction conditions , combinatorial chemistry , catalysis , high performance liquid chromatography , physics , thermodynamics
An efficient synthetic procedure for the functionalized 3,4,10,11‐tetrahydroindolo[1,2‐a]quinoxalines was successfully developed by the three‐component reaction of dimedone, 3‐nitrochromenes, and ammonium acetate in ethanol. This reaction has the advantages of using common starting material, short reaction process, and good yields high‐atom efficiency.