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Microwave‐Assisted Dibromoolefination of Aromatic and Heteroaromatic Aldehydes and Ketones
Author(s) -
Nauroozi Djawed,
Bruhn Clemens,
Fürmeier Sven,
Holzhauer JörnUwe,
Faust Rüdiger
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2332
Subject(s) - chemistry , ketone , microwave irradiation , inert , organic chemistry , microwave chemistry , microwave , scope (computer science) , combinatorial chemistry , catalysis , physics , quantum mechanics , computer science , programming language
Microwave (MW) irradiation was successfully employed to convert aromatic and heteroaromatic aldehydes and ketones efficiently to the corresponding dibromoolefins. Exemplified by the successful dibromoolefination of traditionally inert pyridyl‐flanked carbonyls, MW activation significantly broadens the scope of this valuable transformation, although some limitations especially with electron‐rich aromatic ketone derivatives remain.