Application of  Pfitzinger Reaction  to the Facile One‐Pot Access of the Novel (5,6‐b)‐Quinolino‐8‐carboxylic‐acid‐Annulated Analogs of (2,3‐d)‐Azepino‐benzimidazol‐2,6‐diones of Medicinal Interest | Zendy

Garg Neha | Zendy; Jain Priyanka | Zendy; Kishore D. | Zendy

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Application of Pfitzinger Reaction to the Facile One‐Pot Access of the Novel (5,6‐b)‐Quinolino‐8‐carboxylic‐acid‐Annulated Analogs of (2,3‐d)‐Azepino‐benzimidazol‐2,6‐diones of Medicinal Interest

Author(s) -

Garg Neha,

Jain Priyanka,

Kishore D.

Publication year - 2016

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.2325

Subject(s) - chemistry , combinatorial chemistry , carboxylic acid , reaction conditions , stereochemistry , computational chemistry , medicinal chemistry , organic chemistry , catalysis

The potential of the Pfitzinger reaction has been explored to provide an expedient protocol to the synthesis of novel (5,6‐b)‐quinolino‐8‐carboxylic acid annulated analogues of (2,3‐d)‐azepino benzimidazol‐2,6‐diones 6a , 6b , 6c , 6d , 6e , 6f , 6g from (2,3‐d)‐azepino‐benzimidazol‐2,6,9‐triones 4 and isatins 5a , 5b , 5c , 5d , 5e , 5f , 5g .

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