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Synthesis of Isoxazole, 1, 2, 4‐Oxadiazole and (1 H ‐Pyrazol‐4‐yl)‐methanone Oxime Derivatives from N ‐Hydroxy‐1 H ‐pyrazole‐4‐carbimidoyl Chloride and their Biological Activity
Author(s) -
Sangepu Bhavanarushi,
Gandu Bharath,
Anupoju Gangagnirao,
Jetti Vatsalarani
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2309
Subject(s) - isoxazole , chemistry , pyrazole , oxime , oxadiazole , chloride , proton nmr , medicinal chemistry , carbon 13 nmr , hydroxylamine , stereochemistry , organic chemistry
Some novel isoxazole‐, 1,2,4 oxadiazole‐, and (1 H ‐pyrazol‐4‐yl)‐methanone oxime derivatives were synthesized from N ‐hydroxy‐1 H ‐pyrazole‐4‐carbimidoyl chloride and the structures of all products were identified by spectral data ( 1 H‐NMR, 13 C‐NMR, IR, MS, and HRMS) and evaluated their antibacterial activity .