z-logo
Premium
4‐Hydroxy‐1‐phenylquinolin‐2(1 H )‐one in One‐pot Synthesis of Pyrimidoquinolines and Related Compounds under Microwave Irradiation and Conventional Conditions
Author(s) -
Mourad AboulFetouh E.,
Amer Amer A.,
ElShaieb Kamal M.,
Ali Ali M.,
Aly Ashraf A.
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2286
Subject(s) - chemistry , thiourea , microwave irradiation , benzimidazole , condensation , urea , one pot synthesis , aryl , amine gas treating , medicinal chemistry , microwave , organic chemistry , catalysis , physics , alkyl , quantum mechanics , thermodynamics
Biginelli condensation reactions of 4‐hydroxy‐1‐phenylquinolin‐2(1 H )‐one, aryl aldehydes and urea, or thiourea, 5‐amino‐1 H ‐1,2,4‐triazole, or 2‐amine‐1 H ‐benzimidazole ( 9 ) under microwave irradiation afforded the corresponding pyrimido[5,4‐ c ]quinolin‐5‐one derivatives in high yields. One‐pot synthesis of 2H ‐pyrano[3,2‐ c ]quinolines is also reported.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom