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Synthesis of Some New Heteroylhydrazono‐1,3‐thiazolidin‐4‐ones
Author(s) -
Hassan Alaa A.,
Mohamed Nasr K.,
Abd ElHaleem Lamiaa E.,
Bräse Stefan,
Nieger Martin
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2240
Subject(s) - chemistry , thiophene , condensation , crystal structure , single crystal , medicinal chemistry , stereochemistry , crystallography , organic chemistry , physics , thermodynamics
A series of ( Z )‐methyl‐2‐[( Z )‐3‐substituted‐4‐oxo‐2‐(2‐picolinoyl‐/thiophene‐2‐carbonyl)‐hydrazonothiazolidin‐5‐ylidene]acetates were synthesized by condensation N ‐substituted‐(2‐picolinoyl‐, thiophene‐2‐carbonyl)hydrazinecarbothioamides with dimethylacetylenedicarboxylate. The structure of thiazolidin‐4‐one derivatives has been confirmed unambiguously by single crystal X‐ray crystallography.