A One‐pot, Four‐component Protocol for the Synthesis of 2‐Aroylimino‐3‐aryl‐4‐methyl‐5‐acetyl‐1,3‐thiazolines | Zendy

Saeed Aamer | Zendy; Flörke Ulrich | Zendy

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A One‐pot, Four‐component Protocol for the Synthesis of 2‐Aroylimino‐3‐aryl‐4‐methyl‐5‐acetyl‐1,3‐thiazolines

Author(s) -

Saeed Aamer,

Flörke Ulrich

Publication year - 2015

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.2180

Subject(s) - chemistry , potassium thiocyanate , aryl , component (thermodynamics) , potassium , thiocyanate , medicinal chemistry , organic chemistry , combinatorial chemistry , alkyl , physics , thermodynamics

A concise and efficient route for the synthesis of new 2‐aroylimino‐3‐aryl‐4‐methyl‐5‐acetyl‐1,3‐thiazolines in good to excellent yields is described. This involves the one‐pot, four‐component reaction of suitable aroyl chlorides, potassium thiocyanate, anilines, and 3‐chloropentane‐2,4‐dione in the presence of N ‐methylimidazole.

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