Premium
18‐Crown‐6 Catalyzed Microwave‐mediated Synthesis of Symmetric Bis‐Heterocyclic Compounds under Solvent‐free Condition
Author(s) -
Rishikesan Rathnasamy,
Prabakaran Kamalakannan,
Murugesan Rajamani,
Venkataraman Ramaswamy,
Ranjith Pakkath Karuvalam,
Arvind Sivasubramanian,
Thennarasu Sathiah
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2162
Subject(s) - chemistry , alkyl , amine gas treating , catalysis , pyridine , solvent , biphenyl , medicinal chemistry , organic chemistry
An efficient, solvent‐free and 18‐crown‐6 catalyzed method for the synthesis of N ‐alkyl‐4‐(4‐(5‐(2‐(alkyl‐amino)thiazol‐4‐yl)pyridin‐3‐yl)phenyl)thiazol‐2‐amine, N ‐alkyl‐4‐(5‐(2‐alkyamino)thiazol‐4‐yl)pyridine‐3‐yl)thiazol‐2‐amine, and 4,4′‐bis‐{2‐[amino]‐4‐thiazolyl}biphenyl bis‐heterocyclic derivatives via microwave accelerated cyclization is presented.