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Synthesis of 3‐Butadienyl‐1‐tosylpyrroles
Author(s) -
Settambolo Roberta
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2155
Subject(s) - chemistry , dehydration , tertiary alcohols , combinatorial chemistry , organic chemistry , stereochemistry , alcohol , biochemistry
A pathway for the formation of 3‐butadienyl‐1‐tosylpyrroles from 3‐acyl derivatives via secondary and tertiary 3‐hydroxyalkyl‐1‐tosylpyrroles has been developed. The dehydration of the alcohols intermediates is the crucial step: conditions for high chemo‐ and diastereocontrol are described.
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