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A Simple, Convenient, One‐Pot Synthesis of Dihydro‐azolopyrimidines, DFT Calculation, and NMR Determination by Using H‐Ferrierite Zeolite as Catalyst
Author(s) -
Hassaneen H. M. E.,
Farghaly T. A.
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2152
Subject(s) - chemistry , ferrierite , acetophenone , benzaldehyde , zeolite , catalysis , benzimidazole , computational chemistry , carbon 13 nmr , organic chemistry , proton nmr
The multicomponent reaction of acetophenone derivatives with heterocyclic amines and benzaldehyde derivatives in water in the presence of H‐ferrierite zeolite for short time 8–15 min afforded new series of [1,2,4]triazolo[1,5‐ a ]pyrimidines and pyrimido[1,2‐ a ]benzimidazole derivatives. The structure of the actual tutomeric product was established on the bases of spectral data [IR, NMR ( 1 H and 13 C), and nuclear Overhauser effect] and density functional theory calculations.